As Koppel explains, even something ostensibly simple, such as for example blood-pressure measurement, will get lost in translation because of the modifiers accompanying the amounts: standing, sitting, preinjection, labile, noncompliant. So imagine a common vocabulary for MRI reports or operative notes. Although market influence is indisputable, this explanation conflicts with the impression I got from Judy Faulkner, chief executive officer of EHR maker Epic Systems, who advocates for government-created criteria. Whether or not other vendors are willing to make their products interoperable, government frequently overrides industry’s financial interests to achieve a larger public good.Variant Calling We searched the literature and the Catalog of Somatic Mutations in Tumor and compiled a list of pathogenic variants associated with human hematologic cancers in 160 genes. As a poor control, we also searched for variants which were recurrently observed in nonhematologic cancers .27 Statistical Analysis All the statistical analyses were performed by using the R statistical package . The median age of the persons included in our study at that time DNA was acquired was 58 years ; 8741 were ladies, and 7860 had type 2 diabetes. The identification of somatic driver mutations in cancer has come largely from studies that have compared differences in DNA sequence between tumor and normal tissue obtained from the same person. Once mutations are identified, investigators might genotype samples for these somatic variants without relying on matched normal tissue.